Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 16/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120911 | 0.84 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1 | |
| SCHEMBL8120908 | 0.84 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1 | |
| SCHEMBL8113189 | 0.81 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1 | |
| SCHEMBL9260437 | 0.81 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1 | |
| SCHEMBL8121807 | 0.80 | CYSLTR2 (0.75) | CYSLTR2CYSLTR1 | |
| SCHEMBL8123804 | 0.80 | CYSLTR2 (0.75) | CYSLTR2CYSLTR1 | |
| SCHEMBL8554761 | 0.80 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1 | |
| SCHEMBL8554758 | 0.80 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1 | |
| SCHEMBL8123102 | 0.75 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1 | |
| SCHEMBL8123104 | 0.75 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604114-B1 | Diaryl 5,6-fusedheterocyclic acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 2000-05-03 | — | — | EP | disclosed |
| US-5472964-A | Diaryl 5,6-fused heterocyclic acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1995-12-05 | — | — | US | disclosed |
| WO-1994014815-A1 | DIARYL 5,6-FUSEDHETEROCYCLIC ACIDS AS LEUKOTRIENE ANTAGONISTS | MERCK FROSST CANADA INC. (CA) | 1994-07-07 | — | — | WO | disclosed |
| EP-0604114-A1 | Diaryl 5,6-fusedheterocyclic acids as leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1994-06-29 | — | — | EP | disclosed |