Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113189 | 1.00 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1F2F10 | |
| SCHEMBL8123334 | 0.81 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1 | |
| SCHEMBL8120911 | 0.76 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1 | |
| SCHEMBL8120908 | 0.76 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1 | |
| SCHEMBL8121807 | 0.74 | CYSLTR2 (0.75) | CYSLTR2CYSLTR1 | |
| SCHEMBL8123804 | 0.74 | CYSLTR2 (0.75) | CYSLTR2CYSLTR1 | |
| SCHEMBL9255780 | 0.71 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL9255773 | 0.71 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL8595799 | 0.66 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1 | |
| SCHEMBL8595801 | 0.66 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472964-A | Diaryl 5,6-fused heterocyclic acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1995-12-05 | — | — | US | disclosed |