Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075844 | 0.85 | ALDH1A1 (0.43) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL44951 | 0.72 | — | — | |
| SCHEMBL2075846 | 0.71 | TSHR (0.42) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL28331326 | 0.71 | GAA (0.33) | TSHRIDO1HPGD | |
| Hydrochloric Acid SCHEMBL892263 | 0.70 | KCNH3 (0.47) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| Fluoride SCHEMBL28139765 | 0.70 | PHGDH (0.46) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| Hydrochloric Acid SCHEMBL6761971 | 0.70 | KCNH3 (0.47) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL28771750 | 0.70 | PHGDH (0.46) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL9241215 | 0.70 | KCNH3 (0.43) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| Bicarbonate SCHEMBL10803241 | 0.67 | TSHR (0.50) | TSHRALDH1A1HSD17B10ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344551-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | Basell Polyolefine GmbH (DE) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010034520-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |