Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CASP7 | P55210 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 3/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118207 | 0.86 | ERAP1 (0.72) | KDM4EMAPTHPGDCASP7HSD17B10 | |
| SCHEMBL5082203 | 0.82 | ESR1 (0.82) | KDM4EMAPTHPGDCASP7HSD17B10 | |
| SCHEMBL31675834 | 0.82 | ESR1 (0.82) | KDM4EMAPTHPGDCASP7HSD17B10 | |
| SCHEMBL3366067 | 0.80 | ESR1 (0.88) | KDM4EMAPTHPGDCASP7HSD17B10 | |
| SCHEMBL8934513 | 0.80 | ESR1 (0.88) | KDM4EMAPTHPGDCASP7HSD17B10 | |
| SCHEMBL1800595 | 0.77 | CA1 (0.56) | KDM4EMAPTHPGDCASP7HSD17B10 | |
| SCHEMBL29588932 | 0.76 | MEN1 (0.76) | KDM4EMAPTHPGDCASP7HSD17B10 | |
| SCHEMBL2860609 | 0.76 | MEN1 (0.76) | KDM4EMAPTHPGDCASP7HSD17B10 | |
| SCHEMBL7119204 | 0.75 | CA1 (0.62) | KDM4EAKR1B1ESR1ESR2KMT2A | |
| SCHEMBL7124757 | 0.75 | GABRP (0.59) | MAPTSMN1; SMN2TP53ALOX12CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645382-B1 | COUMARIN DERIVATIVE AND USE THEREOF | MORINAGA MILK INDUSTRY CO LTD (JP) | 2000-07-12 | — | — | EP | disclosed |
| US-5574062-A | COMPOUNDS HAVE 3-ARYL AND 7-HYDROXY OR -ACYLOXY; USE TO INHIBIT 12-LIPOXYGENASE | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0645382-A1 | COUMARIN DERIVATIVE AND USE THEREOF | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |