SCHEMBL8124232

SCHEMBL8124232

CCc1ccc2oc(Cc3ccccc3)c(CCNC(C)=O)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 20/20 1.00
MTNR1B P49286 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8127581 0.89 MTNR1A (0.80) MTNR1AMTNR1B
SCHEMBL8126949 0.89 MTNR1A (0.79) MTNR1AMTNR1B
SCHEMBL8132802 0.88 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL8132560 0.87 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL8132997 0.87 MTNR1A (0.78) MTNR1AMTNR1B
SCHEMBL8116804 0.86 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL8123672 0.85 MTNR1A (0.74) MTNR1AMTNR1B
SCHEMBL8124513 0.85 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL8133077 0.84 MTNR1A (0.74) MTNR1AMTNR1B
SCHEMBL8125310 0.82 MTNR1A (1.00) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1249043-C New heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 2006-04-05 CN disclosed
US-6147110-A MELATONINERGIC AGENTS; SLEEP, EATING, CENTRAL NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS ADIR ET COMPAGNIE (FR) 2000-11-14 US disclosed
EP-0926145-A1 Napthalene compounds, method for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1999-06-30 EP disclosed