Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 20/20 | 0.79 |
| ▸ | MTNR1B | P49286 | 19/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124232 | 0.89 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8125927 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8132560 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8123672 | 0.81 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL8127581 | 0.78 | MTNR1A (0.80) | MTNR1AMTNR1B | |
| SCHEMBL7022296 | 0.78 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8132541 | 0.77 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| SCHEMBL8132802 | 0.77 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8118762 | 0.76 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8132997 | 0.76 | MTNR1A (0.78) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147110-A | MELATONINERGIC AGENTS; SLEEP, EATING, CENTRAL NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-14 | — | — | US | disclosed |
| EP-0926145-A1 | Napthalene compounds, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-30 | — | — | EP | disclosed |