Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 6/20 | 0.58 |
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | VCP | P55072 | 1/20 | 0.58 |
| ▸ | MGAM | O43451 | 1/20 | 0.57 |
| ▸ | SI | P14410 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.57 |
| ▸ | FBP1 | P09467 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HK1 | P19367 | 1/20 | 0.56 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426369 | 1.00 | MAPT (0.66) | MAPTCSNK2A1MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL8356902 | 0.98 | MAPT (0.64) | MAPTCSNK2A1MEN1KMT2AGAA | |
| Bromide SCHEMBL8360677 | 0.98 | MAPT (0.68) | MAPTCSNK2A1MEN1KMT2AGAA | |
| SCHEMBL29654068 | 0.93 | MAPT (0.58) | MAPTCSNK2A1MEN1KMT2AGAA | |
| SCHEMBL25247614 | 0.85 | CSNK2A1 (0.62) | MAPTCSNK2A1MEN1KMT2AGAA | |
| SCHEMBL1806545 | 0.84 | CSNK2A1 (0.61) | MAPTCSNK2A1MEN1KMT2AGAA | |
| SCHEMBL30480033 | 0.84 | CSNK2A1 (0.61) | MAPTCSNK2A1MEN1KMT2AGAA | |
| SCHEMBL7093116 | 0.84 | CSNK2A1 (0.61) | MAPTCSNK2A1MEN1KMT2AGAA | |
| SCHEMBL30294205 | 0.83 | CSNK2A1 (0.71) | MAPTCSNK2A1MEN1KMT2AGAA | |
| SCHEMBL7444589 | 0.82 | CSNK2A1 (0.59) | MAPTCSNK2A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1034176-A1 | THIOPHENE-SULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-13 | — | — | EP | claimed |
| WO-1999028316-A1 | THIOPHENE-SULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | claimed |
| EP-1034176-A1 | THIOPHENE-SULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999028316-A1 | THIOPHENE-SULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |
| CN-1176101-A | N -(4 -aryl -thiazol -2 -yl) -sulphonamide derivatives and their use | HOFFMANN LA ROCHE (CH) | 1998-03-18 | — | — | CN | disclosed |