Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.59 |
| ▸ | VCP | P55072 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431076 | 0.86 | CSNK2A1 (0.56) | CSNK2A1VCPMEN1KMT2AMAPT | |
| SCHEMBL22352682 | 0.84 | MAOA (0.58) | CSNK2A1VCPMEN1KMT2AMAPT | |
| SCHEMBL27908151 | 0.83 | ALDH1A1 (0.65) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7431073 | 0.82 | CSNK2A1 (0.57) | CSNK2A1VCPMEN1KMT2AMAPT | |
| SCHEMBL426369 | 0.82 | MAPT (0.66) | CSNK2A1VCPMEN1KMT2AMAPT | |
| SCHEMBL8124240 | 0.82 | MAPT (0.66) | CSNK2A1VCPMEN1KMT2AMAPT | |
| SCHEMBL24340403 | 0.81 | KMT2A (0.69) | CSNK2A1VCPMEN1KMT2AMAPT | |
| SCHEMBL7091428 | 0.81 | MAPT (0.61) | VCPMEN1KMT2AMAPTALDH1A1 | |
| Bromide SCHEMBL8360677 | 0.81 | MAPT (0.68) | CSNK2A1VCPMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL8356902 | 0.81 | MAPT (0.64) | CSNK2A1VCPMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1034176-A1 | THIOPHENE-SULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-13 | — | — | EP | claimed |
| WO-1999028316-A1 | THIOPHENE-SULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | claimed |
| EP-1034176-A1 | THIOPHENE-SULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999028316-A1 | THIOPHENE-SULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |
| CN-1176101-A | N -(4 -aryl -thiazol -2 -yl) -sulphonamide derivatives and their use | HOFFMANN LA ROCHE (CH) | 1998-03-18 | — | — | CN | disclosed |
| EP-0506194-B1 | 4-aryl-thiazole or imidazole derivatives | AKZO NOBEL NV (NL) | 1996-08-21 | — | — | EP | disclosed |
| US-5462959-A | 4-aryl-imidazole derivatives | AKZO N.V. (NL) | 1995-10-31 | — | — | US | disclosed |
| US-5254575-A | 4-aryl-thiazole derivatives | AKZO N.V. (NL) | 1993-10-19 | — | — | US | disclosed |
| EP-0506194-A1 | 4-aryl-thiazole or imidazole derivatives | Akzo Nobel N.V. (NL) | 1992-09-30 | — | — | EP | disclosed |