Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10330733 | 0.86 | ALDH1A1 (0.45) | ALDH1A1CYP3A4CA1CA2CA9 | |
| SCHEMBL3519353 | 0.84 | CA1 (0.50) | ALDH1A1CYP3A4CA1CA2CA9 | |
| SCHEMBL1205444 | 0.80 | ALDH1A1 (0.39) | ALDH1A1CYP3A4ALDH1A3L3MBTL1POLB | |
| SCHEMBL1312098 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HSD17B10ALDH1A3L3MBTL1 | |
| SCHEMBL2169460 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HSD17B10ALDH1A3L3MBTL1VCAM1 | |
| Fluoride SCHEMBL14358431 | 0.76 | ALDH1A1 (0.54) | ALDH1A1CYP3A4HSD17B10ALDH1A3L3MBTL1 | |
| SCHEMBL574999 | 0.74 | ALDH1A1 (0.52) | ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL8950525 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ALDH1A3L3MBTL1VCAM1 | |
| SCHEMBL6904240 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ALDH1A3L3MBTL1VCAM1 | |
| SCHEMBL28808069 | 0.74 | ALDH1A1 (0.41) | ALDH1A1CYP3A4HSD17B10ALDH1A3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-101379111-A | Polymerizable unsaturated compound and method for producing the same | WAKO PURE CHEM IND LTD (JP) | 2009-03-04 | — | — | CN | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |
| US-5616620-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-04-01 | — | — | US | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |
| US-5216170-A | Promoters of livestock; treatment of obesity | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| US-5028617-A | Heteroarylethanol-pyridylalkylamines for controlling animal growth | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| EP-0379928-A2 | Aryl- and heteroarylethanol-pyridylalkylamines, process for their preparation and their use as performance stimulators by animals and as anti-adipositas agent | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4678797-A | INSECTICIDES, MITICIDES, NEMATOCIDES, FUNGICIDES, FEED UTILIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-07 | — | — | US | disclosed |
| EP-0162383-A1 | Biologically active agent containing substituted isoxazolidines, isoxazolidines and their preparation | BAYER AG (DE) | 1985-11-27 | — | — | EP | disclosed |
| US-4087528-A | POTENTIATORS OF ANTIBACTERIAL SULFA DRUGS | ABBOTT LABORATORIES (US) | 1978-05-02 | — | — | US | disclosed |
| US-4008236-A | 2,4-Diamino-5-benzylpyrimidines | ABBOTT LABORATORIES (US) | 1977-02-15 | — | — | US | disclosed |