Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.75 |
| ▸ | MTNR1B | P49286 | 18/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128191 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4ECYP3A4CYP2D6 | |
| SCHEMBL8127354 | 0.75 | MTNR1A (0.80) | MTNR1AMTNR1BKDM4ECYP3A4CYP2D6 | |
| SCHEMBL6251228 | 0.74 | MTNR1A (0.69) | MTNR1AMTNR1B | |
| SCHEMBL6257501 | 0.74 | MTNR1A (0.69) | MTNR1AMTNR1BKDM4ECYP3A4CYP2D6 | |
| SCHEMBL13436443 | 0.74 | MTNR1A (0.86) | MTNR1AMTNR1BKDM4ECYP3A4CYP2D6 | |
| SCHEMBL8131821 | 0.74 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EHPGDMEN1 | |
| SCHEMBL8131312 | 0.73 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EHPGDMEN1 | |
| SCHEMBL7022296 | 0.72 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8126347 | 0.72 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EHPGDTSHR | |
| SCHEMBL7527814 | 0.72 | KDM4E (0.65) | KDM4ECYP3A4CYP2D6CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147110-A | MELATONINERGIC AGENTS; SLEEP, EATING, CENTRAL NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-14 | — | — | US | claimed |