Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 20/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 20/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127354 | 0.89 | MTNR1A (0.80) | MTNR1AMTNR1BKDM4EALDH1A1CYP3A4 | |
| SCHEMBL8131821 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL8131312 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL8124279 | 0.86 | MTNR1A (0.75) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8126347 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL8124513 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL6251228 | 0.82 | MTNR1A (0.69) | MTNR1AMTNR1B | |
| SCHEMBL6257501 | 0.82 | MTNR1A (0.69) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8133068 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8127311 | 0.80 | MTNR1A (0.76) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147110-A | MELATONINERGIC AGENTS; SLEEP, EATING, CENTRAL NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-14 | — | — | US | disclosed |
| JP-2000239270-A | NEW HETEROCYCLIC COMPOUND, ITS PRODUCTION, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ADIR | 2000-09-05 | — | — | JP | disclosed |
| EP-0926145-A1 | Napthalene compounds, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-30 | — | — | EP | disclosed |