Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 15/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374303 | 0.83 | ABCB1 (1.00) | ABCB1KCNH2 | |
| SCHEMBL1330966 | 0.82 | ABCB1 (1.00) | ABCB1KCNH2 | |
| SCHEMBL30590561 | 0.81 | KCNH2 (1.00) | ABCB1KCNH2 | |
| SCHEMBL8122651 | 0.80 | KCNH2 (1.00) | ABCB1KCNH2 | |
| SCHEMBL1330948 | 0.80 | ABCB1 (1.00) | ABCB1KCNH2 | |
| SCHEMBL31429551 | 0.79 | ABCB1 (0.90) | ABCB1KCNH2 | |
| SCHEMBL29636535 | 0.77 | ABCB1 (0.79) | ABCB1KCNH2 | |
| SCHEMBL31619332 | 0.76 | KCNH2 (0.85) | ABCB1KCNH2 | |
| SCHEMBL8910709 | 0.75 | RAB9A (0.47) | ABCB1 | |
| SCHEMBL8124290 | 0.75 | ABCB1 (0.62) | ABCB1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691962-B1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AG (DE) | 2000-09-13 | — | — | EP | disclosed |
| US-5622953-A | DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| WO-1994022842-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |