Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.68 |
| ▸ | RXRB | P28702 | 16/20 | 0.68 |
| ▸ | RXRG | P48443 | 16/20 | 0.68 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125521 | 0.90 | RXRA (0.55) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8119609 | 0.87 | RXRA (0.53) | RXRARXRBRXRGRARB | |
| SCHEMBL7564779 | 0.85 | RXRA (0.50) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL20411352 | 0.84 | RXRA (0.72) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL17049076 | 0.81 | RXRA (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL11570366 | 0.79 | RXRA (0.62) | RXRARXRBRXRGALDH1A1 | |
| SCHEMBL8118511 | 0.78 | RXRA (0.42) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7565539 | 0.75 | RXRA (0.42) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8461867 | 0.75 | RXRA (0.70) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8116217 | 0.73 | RXRA (0.39) | RXRARXRBRXRGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093838-A | FOR TREATING SKIN-RELATED DISEASES, INCLUDING ACTINIC KERATOSES, ARSENIC KERATOSES, ECZEMA | ALLERGAN SALES, INC. (US) | 2000-07-25 | — | — | US | disclosed |