Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615111 | 0.86 | CYP3A4 (0.41) | ALDH1A1CYP3A4TDP1CYP2D6SMN1; SMN2 | |
| Styrene SCHEMBL28130565 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRHTR2ACYP3A4TDP1 | |
| Styrene SCHEMBL28887829 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRHTR2ACYP3A4PTGS2 | |
| Styrene SCHEMBL29042470 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRCYP3A4TDP1GLA | |
| Styrene SCHEMBL812462 | 0.80 | HTR2A (0.59) | ALDH1A1TSHRHTR2A | |
| SCHEMBL8530818 | 0.78 | — | — | |
| SCHEMBL1958323 | 0.78 | — | — | |
| Styrene SCHEMBL16875726 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRHTR2ACYP3A4TDP1 | |
| Styrene SCHEMBL7201521 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRHTR2ATDP1SMN1; SMN2 | |
| Styrene SCHEMBL28206683 | 0.76 | GPR52 (0.47) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838495-B2 | Rubber composition comprising composite pigment | J.M. HUBER CORPORATION | 2005-01-04 | — | — | US | disclosed |
| WO-2004067617-A1 | RUBBER COMPOSITION COMPRISING COMPOSITE PIGMENT | J.M. HUBER CORPORATION (US) | 2004-08-12 | — | — | WO | disclosed |
| US-20040143050-A1 | Rubber composition comprising composite pigment | J.M. HUBER CORPORATION | 2004-07-22 | — | — | US | disclosed |