Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 5/20 | 0.68 |
| ▸ | PRKCG | P05129 | 5/20 | 0.68 |
| ▸ | PRKCB | P05771 | 5/20 | 0.68 |
| ▸ | PRKCA | P17252 | 5/20 | 0.68 |
| ▸ | PRKCH | P24723 | 5/20 | 0.68 |
| ▸ | PRKCI | P41743 | 5/20 | 0.68 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.68 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.68 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.68 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.68 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.68 |
| ▸ | CDK4 | P11802 | 9/20 | 0.61 |
| ▸ | CCND1 | P24385 | 9/20 | 0.61 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.61 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.61 |
| ▸ | CDK2 | P24941 | 4/20 | 0.61 |
| ▸ | PRKACA | P17612 | 4/20 | 0.60 |
| ▸ | PRKACG | P22612 | 4/20 | 0.60 |
| ▸ | PRKACB | P22694 | 4/20 | 0.60 |
| ▸ | MYLK | Q15746 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127615 | 0.90 | PRKCA (0.54) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9197404 | 0.87 | MYLK (0.62) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9204314 | 0.87 | MYLK (0.63) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8113741 | 0.86 | CDK4 (0.70) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8113301 | 0.85 | MYLK (0.81) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8316417 | 0.81 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL13075769 | 0.79 | CDK4 (0.79) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9834250 | 0.76 | TSHR (0.57) | CDK4CCND1PRKACAPRKACGPRKACB | |
| SCHEMBL8463787 | 0.75 | CDK4 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8120626 | 0.75 | CDK4 (0.80) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642513-B1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | KTB TUMORFORSCHUNGSGESELLSCHAF (DE) | 2000-08-09 | — | — | EP | claimed |
| US-5883114-A | TREATING CANCEROUS TUMORS, INFLAMMATORY DISEASES, AND ALLERGIES | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | claimed |
| EP-0642513-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1995-03-15 | — | — | EP | claimed |
| WO-1993024491-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | claimed |
| EP-0642513-B1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | KTB TUMORFORSCHUNGSGESELLSCHAF (DE) | 2000-08-09 | — | — | EP | disclosed |
| US-5945440-A | Indolocarbazole imides and the use thereof | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |
| US-5883114-A | TREATING CANCEROUS TUMORS, INFLAMMATORY DISEASES, AND ALLERGIES | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| EP-0642513-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024491-A1 | INDOLOCARBAZOLE IMIDES AND THEIR USE | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | disclosed |