Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202591 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPK1FBP1MAPT | |
| SCHEMBL1170985 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPK1FBP1MAPT | |
| SCHEMBL187341 | 0.77 | CYP2C19 (0.43) | ALDH1A1LMNAMAPK1FBP1MAPT | |
| SCHEMBL7025394 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPK1FBP1MAPT | |
| SCHEMBL8932003 | 0.76 | MAPT (0.43) | ALDH1A1LMNAMAPK1FBP1MAPT | |
| SCHEMBL28362063 | 0.74 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPK1FBP1MAPT | |
| SCHEMBL9404111 | 0.74 | KCNN4 (0.42) | ALDH1A1LMNAMAPK1MAPTKMT2A | |
| SCHEMBL1348352 | 0.74 | MAPT (0.42) | ALDH1A1LMNAMAPK1FBP1MAPT | |
| SCHEMBL30013866 | 0.74 | ALDH1A1 (0.42) | ALDH1A1LMNAFBP1MAPTKCNN4 | |
| SCHEMBL5594545 | 0.72 | MAPK1 (0.41) | ALDH1A1LMNAMAPK1FBP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025106-A2 | ALLOSTERIC ADENOSINE RECEPTOR MODULATORS | Medco Research, Inc. (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999021617-A2 | ALLOSTERIC ADENOSINE RECEPTOR MODULATORS | MEDCO RESEARCH, INC. (US) | 1999-05-06 | — | — | WO | disclosed |