Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202591 | 0.79 | ALDH1A1 (0.42) | MAPTKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL187341 | 0.79 | CYP2C19 (0.43) | MAPTKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL1170985 | 0.79 | ALDH1A1 (0.42) | MAPTKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL7025394 | 0.77 | ALDH1A1 (0.41) | MAPTKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL1167741 | 0.76 | ALDH1A1 (0.44) | KMT2AALDH1A1LMNACA12CA2 | |
| SCHEMBL4613619 | 0.76 | ALDH1A1 (0.44) | KMT2AALDH1A1LMNACYP2C19HSD17B10 | |
| SCHEMBL8124997 | 0.76 | ALDH1A1 (0.39) | MAPTKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL1348352 | 0.76 | MAPT (0.42) | MAPTKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL28362063 | 0.76 | ALDH1A1 (0.39) | MAPTKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL9404111 | 0.76 | KCNN4 (0.42) | MAPTKMT2AALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681940-A | CONTAIN TETRAHYDROTHIOPHENE OR PYROLIDINE RINGS | ICN PHARMACEUTICALS (US) | 1997-10-28 | — | — | US | disclosed |