Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424236 | 1.00 | ITGB3 (0.36) | ITGB3ITGA2BAVPR2AVPR1ASMN1; SMN2 | |
| SCHEMBL7419108 | 0.89 | ITGB3 (0.35) | ITGB3ITGA2BAVPR2AVPR1ASMN1; SMN2 | |
| SCHEMBL8125482 | 0.88 | ITGB3 (0.33) | ITGB3ITGA2BAVPR2AVPR1ASMN1; SMN2 | |
| SCHEMBL8118294 | 0.88 | ITGB3 (0.33) | ITGB3ITGA2BAVPR2AVPR1ASMN1; SMN2 | |
| SCHEMBL9029476 | 0.87 | ITGB3 (0.36) | ITGB3ITGA2BAVPR2AVPR1A | |
| SCHEMBL9029463 | 0.87 | ITGB3 (0.36) | ITGB3ITGA2BAVPR2AVPR1A | |
| SCHEMBL8107039 | 0.86 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL8121584 | 0.86 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL8115483 | 0.86 | ITGB3 (0.32) | ITGB3ITGA2B | |
| SCHEMBL8118631 | 0.86 | CYP1A2 (0.35) | ITGB3ITGA2BAVPR2AVPR1AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3034046-B2 | — | — | 2000-04-17 | — | — | JP | claimed |
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | claimed |