Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5233383 | 0.93 | ADORA1 (0.38) | ADORA1ADORA2BADORA2AMEN1GMNN | |
| SCHEMBL8126708 | 0.93 | ADORA2B (0.41) | ADORA1ADORA2BADORA2AMEN1GMNN | |
| Hydrochloric Acid SCHEMBL6094663 | 0.90 | ADORA1 (0.39) | ADORA1ADORA2BADORA2AMEN1GMNN | |
| Hydrochloric Acid SCHEMBL6095290 | 0.90 | ADORA1 (0.39) | ADORA1ADORA2BADORA2AMEN1GMNN | |
| Hydrochloric Acid SCHEMBL5231804 | 0.88 | ADORA1 (0.39) | ADORA1ADORA2BADORA2AMEN1GMNN | |
| Hydrochloric Acid SCHEMBL6092091 | 0.87 | ADORA2B (0.37) | ADORA1ADORA2BADORA2AMEN1GMNN | |
| SCHEMBL8124674 | 0.87 | ADORA1 (0.41) | ADORA1ADORA2BADORA2AMEN1GMNN | |
| Hydrochloric Acid SCHEMBL5232307 | 0.87 | ADORA3 (0.42) | ADORA1ADORA2BADORA2AADORA3PDE5A | |
| Hydrochloric Acid SCHEMBL6092475 | 0.86 | ADORA2B (0.38) | ADORA1ADORA2BADORA2AMEN1GMNN | |
| SCHEMBL6095083 | 0.86 | ADORA2B (0.36) | ADORA1ADORA2BADORA2AMEN1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423805-B1 | Condensed purine derivatives | KYOWA HAKKO KOGYO KK (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5270316-A | Condensed purine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0423805-A2 | Condensed purine derivatives | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1991-04-24 | — | — | EP | disclosed |