Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330186 | 0.83 | AR (0.51) | ARCFTRLMNANPC1CYP1A2 | |
| SCHEMBL8131797 | 0.82 | AR (0.52) | ARCFTRLMNANPC1CYP1A2 | |
| SCHEMBL8125624 | 0.81 | AR (0.57) | ARCFTRLMNANPC1CYP1A2 | |
| SCHEMBL11162148 | 0.79 | LMNA (0.49) | ARCFTRLMNACYP1A2CYP2C9 | |
| SCHEMBL8134460 | 0.78 | AR (0.48) | ARCFTRLMNANPC1CYP1A2 | |
| SCHEMBL5327493 | 0.77 | AR (0.52) | ARCFTRLMNANPC1CYP1A2 | |
| SCHEMBL29412087 | 0.77 | CFTR (0.72) | ARCFTRLMNARAB9AMAPT | |
| SCHEMBL15569406 | 0.77 | CFTR (0.72) | ARCFTRLMNARAB9AMAPT | |
| SCHEMBL5330156 | 0.76 | AR (0.57) | ARCFTRNPC1CYP1A2CYP2C9 | |
| SCHEMBL11099111 | 0.74 | AR (0.52) | ARCFTRMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971747-A2 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998018496-A2 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1998-05-07 | — | — | WO | disclosed |