Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11166536 | 0.95 | PTGDR2 (0.49) | ARCFTRPTGDR2PLA2G2AKDM4E | |
| SCHEMBL5330156 | 0.88 | AR (0.57) | ARCFTRPLA2G2AKDM4EKMT2A | |
| SCHEMBL5327493 | 0.87 | AR (0.52) | ARCFTRKDM4EKMT2AALDH1A1 | |
| SCHEMBL8954292 | 0.87 | ALDH1A1 (0.49) | PTGDR2KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL11093449 | 0.84 | ALDH1A1 (0.48) | PLA2G2AKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL7049490 | 0.84 | DCTPP1 (0.42) | ARCFTRPTGDR2PLA2G2AALDH1A1 | |
| SCHEMBL11094843 | 0.84 | PTGDR2 (0.52) | ARCFTRPTGDR2PLA2G2AKDM4E | |
| SCHEMBL11092145 | 0.84 | LMNA (0.43) | CFTRPLA2G2AKDM4EKMT2AALDH1A1 | |
| SCHEMBL6227119 | 0.83 | ALDH1A1 (0.43) | PLA2G2AKMT2AALDH1A1MEN1 | |
| SCHEMBL5331858 | 0.83 | AR (0.48) | ARCFTRKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56071074-A | — | — | None | — | — | JP | disclosed |
| EP-0028834-B1 | IMIDAZOLE-5-ACETIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-01-18 | — | — | EP | disclosed |
| US-4355040-A | Hypotensive imidazole-5-acetic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| JP-S5671074-A | 1,2-DISUBSTITUTED-4-HALOGENOIMIDAZOLE-5-ACETIC ACID DERIVATIVE | TAKEDA CHEM IND LTD | 1981-06-13 | — | — | JP | disclosed |
| EP-0028834-A1 | Imidazole-5-acetic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-05-20 | — | — | EP | disclosed |