Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213163 | 0.88 | NAPRT (0.67) | NAPRTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29592337 | 0.88 | NAPRT (0.67) | NAPRTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3150862 | 0.82 | NAPRT (0.60) | NAPRTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL991484 | 0.78 | GRM5 (0.59) | NAPRTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3247777 | 0.77 | NAPRT (0.53) | NAPRTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1134961 | 0.76 | LMNA (0.59) | MEN1KMT2AALDH1A1LMNARAB9A | |
| SCHEMBL1877325 | 0.75 | NAPRT (0.60) | NAPRTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL30175321 | 0.75 | NAPRT (0.60) | NAPRTMEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11263672 | 0.75 | LMNA (0.60) | MEN1KMT2AALDH1A1LMNARAB9A | |
| SCHEMBL1742846 | 0.74 | NAPRT (0.53) | NAPRTALDH1A1DGAT1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054881-A1 | NOVEL SULFONAMIDE SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | Bayer Corporation (US) | 2000-11-29 | — | — | EP | disclosed |
| EP-1040106-A1 | CARBOXYL SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA 3 ADRENORECEPTOR AGONISTS | Bayer Corporation (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032475-A1 | NOVEL SULFONAMIDE SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER CORPORATION (US) | 1999-07-01 | — | — | WO | disclosed |
| WO-1999032476-A1 | CARBOXYL SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA 3 ADRENORECEPTOR AGONISTS | BAYER CORPORATION (US) | 1999-07-01 | — | — | WO | disclosed |