SCHEMBL8126451

SCHEMBL8126451

CCn1ncc(C(=O)c2cc(Cl)c3c(c2C)C2(CCSS2)CCS3(=O)=O)c1O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8126454 0.85 RAB9A (0.35) RAB9ASMN1; SMN2
SCHEMBL8128408 0.82 RAB9A (0.35) RAB9ASMN1; SMN2
SCHEMBL8129451 0.80
SCHEMBL8122957 0.79
SCHEMBL8138238 0.78 CYP4F2 (0.33)
SCHEMBL6721441 0.77 SMN1; SMN2 (0.34) RAB9ASMN1; SMN2
SCHEMBL7842848 0.73 SMN1; SMN2 (0.37) RAB9ASMN1; SMN2
SCHEMBL8941036 0.72 RAB9A (0.33) RAB9ASMN1; SMN2
SCHEMBL8014294 0.72 RAB9A (0.32) RAB9ASMN1; SMN2
SCHEMBL8014291 0.72 RAB9A (0.32) RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6159904-A Pyrazole derivatives IDEMITSU KOSAN CO., LTD. (JP) 2000-12-12 US disclosed
EP-0970956-A1 PYRAZOLE DERIVATIVES IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-01-12 EP disclosed