Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252804 | 0.76 | TP53 (0.45) | KDM4ETAAR1 | |
| SCHEMBL79967 | 0.74 | ALDH1A1 (0.38) | MAPK1 | |
| SCHEMBL81248 | 0.72 | HRH3 (0.65) | HRH3CNR2KDM4ETSHRMAPK1 | |
| SCHEMBL6252586 | 0.72 | HPGD (0.40) | KDM4ETSHRL3MBTL1ACHEMAOB | |
| SCHEMBL10018834 | 0.70 | ALDH1A1 (0.41) | TAAR1TSHRMAPK1 | |
| Fluoride SCHEMBL11307410 | 0.70 | HRH3 (0.62) | HRH3CNR2KDM4ETSHRMAPK1 | |
| Water SCHEMBL5507580 | 0.70 | HRH3 (0.62) | HRH3CNR2KDM4ETSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL890978 | 0.70 | HRH3 (0.62) | HRH3CNR2KDM4ETSHRMAPK1 | |
| Iodide SCHEMBL21693881 | 0.70 | HRH3 (0.62) | HRH3CNR2KDM4ETSHRMAPK1 | |
| Bromide SCHEMBL11663269 | 0.70 | HRH3 (0.62) | HRH3CNR2KDM4ETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9279806-B2 | Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-08 | — | — | US | disclosed |
| US-20150031607-A1 | WATER-SOLUBLE AIE LUMINOGENS FOR MONITORING AND RETARDATION OF FIBRILLATION OF AMYLOID PROTEINS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-01-29 | — | — | US | disclosed |
| US-8679738-B2 | Water-soluble AIE luminogen for monitoring and retardation of amyloid fibrillation of insulin | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-03-25 | — | — | US | disclosed |
| US-8263018-B2 | Detecting aggregation-induced emission via fluorescence | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2012-09-11 | — | — | US | disclosed |
| US-20120172296-A1 | WATER-SOLUBLE AIE LUMINOGEN FOR MONITORING AND RETARDATION OF AMYLOID FIBRILLATION OF INSULIN | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2012-07-05 | — | — | US | disclosed |
| US-8129111-B2 | Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2012-03-06 | — | — | US | disclosed |
| US-7939613-B2 | Probes/sensors for biomacromolecules; films; cosmetics | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2011-05-10 | — | — | US | disclosed |
| US-20100009362-A1 | Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-01-14 | — | — | US | disclosed |
| US-20080220407-A1 | Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172296-A1 | WATER-SOLUBLE AIE LUMINOGEN FOR MONITORING AND RETARDATION OF AMYLOID FIBRILLATION OF INSULIN | IAPP, IGF2BP1, IGF2BP2 | HRH3 4353/4885CNR2 4429/4885OPRD1 4205/4885 |
| US-20080220407-A1 | Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | FUS, CD63, EPCAM | HRH3 4206/4885CNR2 4282/4885OPRD1 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.