Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.30 |
| ▸ | ITGAV | P06756 | 2/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112600 | 0.89 | ITGB3 (0.33) | MEN1KMT2ATDP1ITGB3ITGA2B | |
| SCHEMBL7750605 | 0.88 | NPY1R (0.33) | MEN1KMT2ATDP1ITGB3ITGA2B | |
| SCHEMBL4653096 | 0.85 | ITGB3 (0.33) | ITGB3ITGA2BITGAV | |
| SCHEMBL7751629 | 0.85 | NR1H3 (0.40) | MEN1KMT2ANR1H3TDP1ITGB3 | |
| Iodide SCHEMBL8585363 | 0.85 | NPY1R (0.37) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL8584075 | 0.79 | NPY1R (0.36) | — | |
| SCHEMBL8120102 | 0.78 | MEN1 (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL8127520 | 0.77 | NPY1R (0.45) | — | |
| SCHEMBL7746039 | 0.76 | ITGB3 (0.33) | ITGB3ITGA2BITGAV | |
| SCHEMBL6897903 | 0.72 | EPOR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |