Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275404 | 0.88 | KMT2A (0.46) | MTNR1AFAAHKMT2AMEN1KDM4E | |
| SCHEMBL4651833 | 0.83 | CNR1 (0.47) | KMT2AMEN1KDM4EALDH1A1BLM | |
| SCHEMBL4651007 | 0.83 | HAT1 (0.45) | MTNR1AMTNR1BKMT2ATDP1 | |
| SCHEMBL1132070 | 0.80 | MTNR1A (0.65) | MTNR1AMTNR1BTRPV1FAAHKMT2A | |
| SCHEMBL4651777 | 0.79 | CNR1 (0.48) | ALDH1A1 | |
| SCHEMBL4651881 | 0.79 | CTSD (0.43) | MTNR1AMTNR1BALDH1A1TDP1POLB | |
| SCHEMBL9275211 | 0.78 | KMT2A (0.45) | FAAHKMT2AMEN1CYP1A2RAB9A | |
| SCHEMBL4097952 | 0.77 | MTNR1A (0.78) | MTNR1AMTNR1BFAAHKMT2AMEN1 | |
| SCHEMBL8120358 | 0.75 | CNR1 (0.51) | MTNR1AMTNR1B | |
| SCHEMBL4652031 | 0.74 | NPY1R (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |