Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127086 | 0.84 | TLR7 (0.41) | TLR7POLB | |
| SCHEMBL8142202 | 0.82 | TLR7 (0.46) | TLR7POLB | |
| SCHEMBL3863867 | 0.82 | TLR7 (0.49) | TLR7POLB | |
| SCHEMBL13937509 | 0.79 | TLR7 (0.50) | TLR7POLB | |
| SCHEMBL13937503 | 0.78 | TLR7 (0.49) | TLR7POLB | |
| SCHEMBL13937480 | 0.78 | TLR7 (0.49) | TLR7POLB | |
| SCHEMBL8136478 | 0.78 | TLR7 (0.46) | ALDH1A1TLR7POLB | |
| SCHEMBL5748435 | 0.78 | TLR7 (0.49) | TLR7POLBMAPTTP53BCHE | |
| SCHEMBL8140138 | 0.78 | TLR7 (0.48) | TLR7POLB | |
| SCHEMBL8132936 | 0.78 | TLR7 (0.46) | TLR7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069149-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | TERUMO KABUSHIKI KAISHA (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0894797-A1 | NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1999-02-03 | — | — | EP | disclosed |