Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15185145 | 0.85 | NPC1 (0.48) | SMN1; SMN2PARP1PSEN1PSEN2APH1B | |
| SCHEMBL1643399 | 0.84 | HTR2C (0.52) | SMN1; SMN2CYP2C19PARP1PSEN1PSEN2 | |
| SCHEMBL13073095 | 0.84 | HTR2C (0.52) | SMN1; SMN2CYP2C19PARP1PSEN1PSEN2 | |
| SCHEMBL13032699 | 0.84 | ELANE (0.48) | SMN1; SMN2PARP1PSEN1PSEN2APH1B | |
| SCHEMBL17495268 | 0.82 | PDK1 (0.45) | SMN1; SMN2PARP1PSEN1PSEN2APH1B | |
| SCHEMBL3823845 | 0.81 | NPC1 (0.50) | SMN1; SMN2CYP2C19PARP1PSEN1PSEN2 | |
| SCHEMBL30440090 | 0.81 | FKBP1A (0.50) | SMN1; SMN2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23478113 | 0.80 | PSEN1 (0.62) | SMN1; SMN2CYP2C19PARP1PSEN1PSEN2 | |
| SCHEMBL29906748 | 0.80 | PARP1 (0.49) | SMN1; SMN2CYP2C19PARP1PSEN1PSEN2 | |
| SCHEMBL2391599 | 0.79 | AOC3 (0.52) | SMN1; SMN2CYP2C19PARP1PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968734-B2 | Organocatalysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-06-28 | — | — | US | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | SCO2, CBR1, CBR3 | SMN1; SMN2 3982/4885CYP2C19 378/4885PARP1 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.