Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133893 | 0.85 | KMT2A (0.47) | GAAKMT2AMAOBMEN1MAOA | |
| SCHEMBL8121689 | 0.85 | APP (0.47) | GAAKMT2AMAOBMEN1KDM4E | |
| SCHEMBL8127562 | 0.84 | APP (0.46) | GAAKMT2AMAOBMEN1KDM4E | |
| SCHEMBL8128029 | 0.82 | KDM4E (0.49) | GAAKMT2AMAOBMEN1KDM4E | |
| SCHEMBL9513053 | 0.82 | MAOB (0.51) | MAOBKDM4ETP53CYP2D6HTT | |
| SCHEMBL8124088 | 0.82 | APP (0.43) | GAAKMT2AMAOBMEN1KDM4E | |
| SCHEMBL8128215 | 0.79 | KDM4E (0.44) | GAAKMT2AMAOBMEN1KDM4E | |
| SCHEMBL9512074 | 0.79 | MAOB (0.48) | MAOBKDM4ETP53CYP2D6HTT | |
| SCHEMBL8122410 | 0.78 | KDM4E (0.41) | GAAKMT2AMAOBMEN1KDM4E | |
| SCHEMBL8102697 | 0.78 | MAOB (0.51) | GAAKMT2AMAOBMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006108-A1 | 3-Hydroxy-2(1H)-pyridinone or 3-hydroxy-4(1H)-pyridinone derivatives useful as reactive oxygen species (ROS) scavengers | Cerebrus Pharmaceuticals Limited (GB) | 2000-06-07 | — | — | EP | disclosed |