Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP13 | P45452 | 4/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 3/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121462 | 0.89 | ALDH1A1 (0.38) | ALDH1A1GAASMN1; SMN2TSHRGFER | |
| SCHEMBL8127349 | 0.80 | FLT1 (0.35) | ALDH1A1GAASMN1; SMN2FFAR4TSHR | |
| SCHEMBL7689686 | 0.77 | ALDH1A1 (0.66) | ALDH1A1GAASMN1; SMN2FFAR4TSHR | |
| SCHEMBL8114015 | 0.73 | ALDH1A1 (0.40) | ALDH1A1GAASMN1; SMN2TSHRGFER | |
| SCHEMBL7682903 | 0.71 | FLT1 (0.39) | ALDH1A1GAAFFAR4TSHRGFER | |
| SCHEMBL8129934 | 0.71 | TP53 (0.43) | ALDH1A1GAAFFAR4TSHRGFER | |
| SCHEMBL8122275 | 0.71 | ALDH1A1 (0.38) | ALDH1A1GAASMN1; SMN2FFAR4TSHR | |
| SCHEMBL8121989 | 0.65 | ALDH1A1 (0.40) | ALDH1A1GAASMN1; SMN2TSHRGFER | |
| SCHEMBL2788247 | 0.63 | CA1 (0.70) | ALDH1A1GAASMN1; SMN2FFAR4GFER | |
| SCHEMBL7681176 | 0.62 | TP53 (0.49) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |