Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.44 |
| ▸ | MC1R | Q01726 | 5/20 | 0.44 |
| ▸ | MC3R | P41968 | 4/20 | 0.44 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.42 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 3/20 | 0.41 |
| ▸ | NPY1R | P25929 | 7/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128352 | 0.85 | PADI4 (0.39) | MC4RMC1RMC3RPADI4PADI2 | |
| SCHEMBL5057899 | 0.82 | NPY1R (0.53) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL4650707 | 0.82 | NPY1R (0.43) | MC4RMC1RMC3RNPY1RTLR2 | |
| SCHEMBL1388313 | 0.82 | NPY1R (0.44) | MC4RMC1RMC3RNPY1RTLR2 | |
| SCHEMBL4651114 | 0.81 | NPY1R (0.45) | MC4RMC1RMC3RNPY1RTLR2 | |
| SCHEMBL4651537 | 0.81 | CYP3A4 (0.46) | MC4RMC1RMC3RNPY1RTLR2 | |
| SCHEMBL1388761 | 0.80 | NPY1R (0.51) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL4651777 | 0.79 | CNR1 (0.48) | MC4RMC1RMC3RNPY1RTLR2 | |
| SCHEMBL4651789 | 0.79 | TRPV1 (0.43) | MC4RMC1RMC3RNPY1R | |
| SCHEMBL4651881 | 0.79 | CTSD (0.43) | MC4RMC1RMC3RTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |