Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130242 | 0.87 | PARP1 (0.33) | PARP1 | |
| SCHEMBL8566838 | 0.87 | PARP1 (0.33) | PARP1 | |
| SCHEMBL8570853 | 0.82 | PARP1 (0.34) | PARP1PARP2 | |
| SCHEMBL8565685 | 0.82 | PARP1 (0.34) | PARP1PARP2 | |
| SCHEMBL8120739 | 0.79 | PARP1 (0.39) | PARP1PARP2 | |
| Hydrochloric Acid SCHEMBL8120773 | 0.78 | KDM4E (0.38) | PARP1 | |
| SCHEMBL8564031 | 0.77 | CDC7 (0.32) | PARP1PARP2 | |
| SCHEMBL8567997 | 0.77 | CDC7 (0.32) | PARP1PARP2 | |
| SCHEMBL8114887 | 0.74 | PARP1 (0.30) | PARP1PARP2 | |
| SCHEMBL8128876 | 0.73 | PTGER3 (0.32) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973777-A1 | FUROPYRIDINE, THIENOPYRIDINE, PYRROLOPYRIDINE AND RELATED PYRIMIDINE, PYRIDAZINE AND TRIAZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-01-26 | — | — | EP | claimed |
| WO-1998046609-A1 | FUROPYRIDINE, THIENOPYRIDINE, PYRROLOPYRIDINE AND RELATED PYRIMIDINE, PYRIDAZINE AND TRIAZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1998-10-22 | — | — | WO | claimed |
| EP-0842178-A1 | FUROPYRIDINE, THIENOPYRIDINE, PYRROLOPYRIDINE AND RELATED PYRIMIDINE, PYRIDAZINE AND TRIAZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005139-A1 | FUROPYRIDINE, THIENOPYRIDINE, PYRROLOPYRIDINE AND RELATED PYRIMIDINE, PYRIDAZINE AND TRIAZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1997-02-13 | — | — | WO | disclosed |