Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130242 | 1.00 | PARP1 (0.33) | PARP1 | |
| SCHEMBL8128487 | 0.87 | PARP1 (0.34) | PARP1 | |
| SCHEMBL8565685 | 0.80 | PARP1 (0.34) | PARP1 | |
| SCHEMBL8570853 | 0.80 | PARP1 (0.34) | PARP1 | |
| SCHEMBL8114887 | 0.77 | PARP1 (0.30) | PARP1 | |
| SCHEMBL8120739 | 0.77 | PARP1 (0.39) | PARP1 | |
| Hydrochloric Acid SCHEMBL8120773 | 0.76 | KDM4E (0.38) | PARP1 | |
| SCHEMBL8567997 | 0.75 | CDC7 (0.32) | PARP1 | |
| SCHEMBL8564031 | 0.75 | CDC7 (0.32) | PARP1 | |
| SCHEMBL8567488 | 0.70 | CHRNB2 (0.45) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842178-A1 | FUROPYRIDINE, THIENOPYRIDINE, PYRROLOPYRIDINE AND RELATED PYRIMIDINE, PYRIDAZINE AND TRIAZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005139-A1 | FUROPYRIDINE, THIENOPYRIDINE, PYRROLOPYRIDINE AND RELATED PYRIMIDINE, PYRIDAZINE AND TRIAZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1997-02-13 | — | — | WO | disclosed |