SCHEMBL812849

SCHEMBL812849

[C-]#[N+]C(C(C)=O)=C(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.50
CES1 P23141 2/20 0.50
CA1 P00915 6/20 0.48
CA2 P00918 6/20 0.48
MAPT P10636 3/20 0.47
PARP10 Q53GL7 2/20 0.47
PARP1 P09874 1/20 0.47
PARP2 Q9UGN5 1/20 0.47
PARP4 Q9UKK3 1/20 0.47
LMNA P02545 2/20 0.46
HPGD P15428 2/20 0.46
MAPK1 P28482 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
ESR1 P03372 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46
ADRA1A P35348 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10453225 0.90 SMN1; SMN2 (0.41) CES2CES1CA1CA2MAPT
SCHEMBL2957320 0.72 ALDH1A1 (0.70) CES2CES1CA1CA2MAPT
SCHEMBL2320546 0.71 CES2 (0.78) CES2CES1CA1CA2MAPT
SCHEMBL9982878 0.71 CES2 (0.64) CES2CES1CA1CA2MAPT
P-Methoxy-Acetophenone SCHEMBL41285 0.71 MAPT (0.70) CES2CES1CA1CA2MAPT
SCHEMBL8937548 0.71 CA1 (0.61) CES2CES1CA1CA2MAPT
P-Methoxy-Acetophenone SCHEMBL9835038 0.69 MAPT (0.67) CES2CES1CA1CA2MAPT
P-Methoxy-Acetophenone SCHEMBL27841741 0.69 MAPT (0.67) CES2CES1CA1CA2MAPT
P-Methoxy-Acetophenone SCHEMBL27967967 0.69 MAPT (0.67) CES2CES1CA1CA2MAPT
P-Methoxy-Acetophenone SCHEMBL27814658 0.69 MAPT (0.67) CES2CES1CA1CA2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9091804-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2015-07-28 US disclosed
US-8445081-B2 Polarizing plate protective film, polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2013-05-21 US disclosed
US-8425991-B2 Cellulose acylate film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
US-8377344-B2 comprising thermoplastic resins or cellulose acetates, mixed with sulfonamides or tertiary amides, used as protecting coatings for polarizing plates and as adjustment films for display panels to improve viewing angles FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-8354148-B2 Optical compensation polarizing plate, image display unit and liquid crystal display unit FUJIFILM CORPORATION (JP) 2013-01-15 US disclosed
US-8313814-B2 Cellulose acylate film, method of producing the same, cellulose derivative film, optically compensatory film using the same, optically-compensatory film incorporating polarizing plate, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-11-20 US disclosed
US-8199291-B2 Liquid crystal display device having polymer-stabilized blue phase liquid crystal layer and transparent films FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-8187681-B2 Transparent film and optical compensatory film, polarizing plate and liquid-crystal display device employing it FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-8062562-B2 Method of producing a cellulose ester film KONICA MINOLTA OPTO, INC. (JP) 2011-11-22 US disclosed
US-8059240-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2011-11-15 US disclosed
US-20080043177-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-02-21 US disclosed
US-7318951-B2 Retardation film, producing process thereof and liquid crystal display utilizing the same FUJIFILM CORPORATION (JP) 2008-01-15 US disclosed
US-20070292635-A1 Optical Compensation Polarizing Plate, Image Display Unit and Liquid Crystal Display Unit FUJIFILM CORPORATION (JP) 2007-12-20 US disclosed
US-20070285603-A1 Transparent Film And Optical Compensatory Film, Polarizing Plate And Liquid-Crystal Display Device Employing It FUJI PHOTO FILM CO., LTD. (JP) 2007-12-13 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070092663-A1 Cellulose ester film, polarizing plate and display KONICA MINOLTA OPTO, INC. 2007-04-26 US disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed
US-20070048458-A1 Optical film, method of producing the same, optical compensatory film, polarizing film, and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-01 US disclosed
US-20070040962-A1 Optical resin film and polarizing plate and liquid crystal display using same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 US disclosed