Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128996 | 1.00 | PPARG (0.47) | PPARGPPARAKDRHPGDFFAR1 | |
| SCHEMBL10365494 | 0.86 | HPGD (0.61) | PPARGPPARAHPGDFFAR1PTPN1 | |
| SCHEMBL10365493 | 0.86 | HPGD (0.61) | PPARGPPARAHPGDFFAR1PTPN1 | |
| SCHEMBL6972649 | 0.83 | KDR (0.48) | PPARGPPARAKDRHPGDFFAR1 | |
| SCHEMBL8122331 | 0.82 | KDR (0.56) | PPARGPPARAKDRFFAR1PTPN1 | |
| SCHEMBL6973022 | 0.81 | PPARG (0.47) | PPARGPPARAKDRHPGDFFAR1 | |
| SCHEMBL8337047 | 0.81 | PPARG (0.47) | PPARGPPARAKDRHPGDFFAR1 | |
| SCHEMBL8139624 | 0.79 | KDR (0.53) | PPARGPPARAKDRFFAR1PTPN1 | |
| SCHEMBL8139628 | 0.79 | KDR (0.53) | PPARGPPARAKDRFFAR1PTPN1 | |
| SCHEMBL8141923 | 0.79 | KCNH2 (0.50) | PPARGPPARAHPGDPTPN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733631-B1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-07-12 | — | — | EP | claimed |
| EP-0733631-A1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | Takeda Chemical Industries, Ltd. (JP) | 1996-09-25 | — | — | EP | claimed |
| EP-0733631-B1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-07-12 | — | — | EP | disclosed |
| US-5723479-A | ANTILIPEMIC AGENTS AND ANTIGLYCEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0733631-A1 | Benzofuran derivates useful as hypoglycemic and hypolidemic agents | Takeda Chemical Industries, Ltd. (JP) | 1996-09-25 | — | — | EP | disclosed |