Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 18/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127195 | 0.84 | KDM4E (0.40) | MAOB | |
| SCHEMBL8119210 | 0.83 | APP (0.40) | MAOB | |
| SCHEMBL8652699 | 0.78 | ALOX5 (0.32) | — | |
| SCHEMBL8136363 | 0.77 | APP (0.37) | MAOB | |
| SCHEMBL8652066 | 0.76 | ALOX5 (0.36) | — | |
| SCHEMBL8131655 | 0.74 | PTGS1 (0.52) | MAOB | |
| SCHEMBL8130061 | 0.69 | CYP4F2 (0.42) | MAOB | |
| SCHEMBL29842394 | 0.69 | TSHR (0.39) | — | |
| SCHEMBL6885035 | 0.69 | TSHR (0.39) | — | |
| SCHEMBL8118001 | 0.69 | HTT (0.50) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006108-A1 | 3-Hydroxy-2(1H)-pyridinone or 3-hydroxy-4(1H)-pyridinone derivatives useful as reactive oxygen species (ROS) scavengers | Cerebrus Pharmaceuticals Limited (GB) | 2000-06-07 | — | — | EP | disclosed |