Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP4 | P49662 | 1/20 | 0.30 |
| ▸ | CASP5 | P51878 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652066 | 0.93 | ALOX5 (0.36) | ALOX5PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL6885035 | 0.79 | TSHR (0.39) | ALOX5PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9214227 | 0.79 | MIF (0.39) | ALOX5PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9205106 | 0.76 | MTNR1A (0.36) | ALOX5PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9210153 | 0.76 | ALOX5 (0.42) | ALOX5PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8136061 | 0.76 | ALOX5 (0.42) | ALOX5PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9210232 | 0.73 | ALOX5 (0.38) | ALOX5PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9210238 | 0.73 | ALOX5 (0.38) | ALOX5PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9203503 | 0.73 | ALOX5 (0.44) | ALOX5PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8598222 | 0.70 | ALOX5 (0.47) | ALOX5PTGS1PTGS2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6234756-A | — | — | None | — | — | JP | disclosed |
| EP-0604995-B1 | Hydroxyamines N-acyl derivatives having scavenger activity and useful in acute and chronic pathologies associated with peroxidation and inflammation phenomena | LIFEGROUP SPA (IT) | 1998-09-30 | — | — | EP | disclosed |
| US-5480645-A | Hydroxyamines N-acyl derivatives having scavenger activity and useful in acute and chronic pathologies associated with peroxidation and inflammation phenomena | LIFEGROUP S.P.A. (IT) | 1996-01-02 | — | — | US | disclosed |
| JP-H06234756-A | HYDROXYAMINE N-ACYL DERIVATIVE HAVING SCAVENGER ACTIVITY AND USEFUL IN ACUTE AND CHRONIC PATHOLOGY ASSOCIATED WITH PEROXIDATION AND INFLAMMATION PHENOMENA | LIFEGROUP SPA | 1994-08-23 | — | — | JP | disclosed |
| EP-0604995-A1 | Hydroxyamines N-acyl derivatives having scavenger activity and useful in acute and chronic pathologies associated with peroxidation and inflammation phenomena | LIFEGROUP S.p.A. (IT) | 1994-07-06 | — | — | EP | disclosed |