Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | APEX1 | P27695 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145874 | 0.81 | BLM (0.57) | CYP3A4MAPTTDP1APEX1RECQL | |
| SCHEMBL20716304 | 0.79 | PDE3B (0.32) | CYP3A4MAPTTDP1APEX1RECQL | |
| SCHEMBL27685164 | 0.77 | CYP3A4 (0.50) | CYP3A4BLMALDH1A1TSHRPMP22 | |
| SCHEMBL8770931 | 0.76 | L3MBTL1 (0.37) | MAPTTDP1RECQLBLMKDM4E | |
| SCHEMBL6746791 | 0.75 | ALDH1A1 (0.45) | CYP3A4MAPTMEN1KMT2AADRB2 | |
| SCHEMBL6741460 | 0.75 | ALDH1A1 (0.45) | CYP3A4MAPTMEN1KMT2AADRB2 | |
| SCHEMBL83311 | 0.75 | HTR2A (0.45) | MEN1KMT2ALMNASLC6A2SLC6A4 | |
| SCHEMBL27504138 | 0.75 | HTR2A (0.45) | MEN1KMT2ALMNASLC6A2SLC6A4 | |
| SCHEMBL918222 | 0.75 | HTR2A (0.45) | MEN1KMT2ALMNASLC6A2SLC6A4 | |
| SCHEMBL2754733 | 0.74 | SLC18A3 (0.46) | CYP3A4MAPTADRB2ADRB1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156940-A | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0713848-B1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS COMPANY (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5831132-A | REDUCING AGENT FROM BORANES AND AMINO ALCOHOLS | SUMIKA FINE CHEMICALS COMPANY, LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0713848-A1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1996-05-29 | — | — | EP | disclosed |