Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27536627 | 0.91 | FFAR1 (0.47) | FFAR1OPRD1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL1697227 | 0.77 | SLC6A2 (0.59) | OPRD1CACNA2D1CACNA1BCACNB1SOS1 | |
| SCHEMBL27626466 | 0.77 | FFAR1 (0.50) | FFAR1OPRD1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL5652288 | 0.76 | MEN1 (0.58) | FFAR1MEN1KMT2APKMCTDSP1 | |
| SCHEMBL6193810 | 0.75 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL5316106 | 0.74 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9381630 | 0.73 | SOS1 (0.45) | OPRD1SOS1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL93039 | 0.73 | OPRD1 (0.48) | OPRD1SOS1PKMCTDSP1SLC6A2 | |
| SCHEMBL27775280 | 0.72 | CPN1 (0.42) | OPRD1 | |
| Hydrochloric Acid SCHEMBL8786951 | 0.72 | SLC6A2 (0.47) | OPRD1SOS1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1039899-A2 | PHARMACEUTICAL COMPOSITION FOR ANTAGONIZING CCR5 COMPRISING ANILIDE DERIVATIVE | Takeda Chemical Industries, Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032100-A2 | PHARMACEUTICAL COMPOSITION FOR ANTAGONIZING CCR5 COMPRISING ANILIDE DERIVATIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |