Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26629764 | 0.83 | PKM (0.55) | PKMCTDSP1 | |
| SCHEMBL27391812 | 0.83 | PKM (0.59) | SLC6A2SLC6A4SLC6A3PKMCTDSP1 | |
| SCHEMBL9381630 | 0.82 | SOS1 (0.45) | OPRD1SLC6A2SLC6A4SLC6A3SOS1 | |
| SCHEMBL1697227 | 0.82 | SLC6A2 (0.59) | OPRD1SLC6A2SLC6A4SLC6A3SOS1 | |
| SCHEMBL2465315 | 0.81 | PKM (0.62) | SLC6A2SLC6A3PKMCTDSP1 | |
| Hydrochloric Acid SCHEMBL8786951 | 0.81 | SLC6A2 (0.47) | OPRD1SLC6A2SLC6A4SLC6A3SOS1 | |
| SCHEMBL5781131 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3SOS1 | |
| Methyl Alcohol SCHEMBL27363776 | 0.80 | PKM (0.56) | SLC6A2SLC6A3PKMCTDSP1 | |
| SCHEMBL22863375 | 0.79 | PKM (0.44) | PKMCTDSP1 | |
| SCHEMBL9346690 | 0.79 | PKM (0.44) | PKMCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129409-B2 | Piperidine derivatives and cosmetic compositions thereof | L'OREAL (FR) | 2012-03-06 | — | — | US | disclosed |
| US-20100267770-A1 | PIPERIDINE DERIVATIVES AND COSMETIC COMPOSITIONS THEREOF | L'OREAL (FR) | 2010-10-21 | — | — | US | disclosed |
| US-7807695-B2 | Cosmetic use of piperidine derivatives | L'OREAL (FR) | 2010-10-05 | — | — | US | disclosed |
| US-20100056530-A1 | GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2010-03-04 | — | — | US | disclosed |
| US-20080090866-A1 | Cosmetic Use of Piperidine Derivatives | L'OREAL (FR) | 2008-04-17 | — | — | US | disclosed |
| CN-1243567-C | Growth hormone secretagogues | LILLY CO ELI (US) | 2006-03-01 | — | — | CN | disclosed |
| CN-1276727-A | Growth hormone secretagogues | LILLY CO ELI (US) | 2000-12-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267770-A1 | PIPERIDINE DERIVATIVES AND COSMETIC COMPOSITIONS THEREOF | TRPA1, PLIN5, SRM | OPRD1 64/4885SLC6A2 4003/4885SLC6A4 2807/4885 |
| US-20100056530-A1 | GLUCOKINASE ACTIVATORS | GCKR, GCK, GALK1 | OPRD1 3821/4885SLC6A2 4198/4885SLC6A4 4110/4885 |
| US-20080090866-A1 | Cosmetic Use of Piperidine Derivatives | TRPA1, TRPV5, CUTA | OPRD1 806/4885SLC6A2 3624/4885SLC6A4 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.