Pyridine

Pyridine

SCHEMBL8129309

C=C(CO)C(=O)OCC.c1ccncc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
MAPT P10636 3/20 0.42
TSHR P16473 1/20 0.42
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CTDSP1 Q9GZU7 1/20 0.36
XPO1 O14980 2/20 0.34
CDC7 O00311 2/20 0.34
DBF4 Q9UBU7 2/20 0.34
CASP1 P29466 2/20 0.34
GAA P10253 2/20 0.33
PKM P14618 1/20 0.33
THRB P10828 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
KDM4E B2RXH2 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL8128217 0.84 ALDH1A1 (0.46) ALDH1A1MAPTTSHRMEN1KMT2A
SCHEMBL36653 0.83
Pyridine SCHEMBL8119711 0.82 THRB (0.52) ALDH1A1MAPTTSHRMEN1KMT2A
Toluene SCHEMBL27561078 0.79 ALDH1A1 (0.54) ALDH1A1MAPTTSHRMEN1KMT2A
Methacrylic Acid SCHEMBL2458636 0.78 ALDH1A1 (0.42) ALDH1A1MAPTTSHRMEN1KMT2A
Pyridine SCHEMBL28512949 0.78 ALDH1A1 (0.41) ALDH1A1MAPTTSHRMEN1KMT2A
Furan SCHEMBL28233665 0.77 ALDH1A1 (0.40) ALDH1A1MAPTTSHRMEN1KMT2A
Phthalic Acid SCHEMBL19458044 0.77 ALDH1A1 (0.51) ALDH1A1MAPTTSHRMEN1KMT2A
Pyridine SCHEMBL27786003 0.77 MEN1 (0.41) ALDH1A1MAPTTSHRMEN1KMT2A
SCHEMBL3255275 0.76 ALDH1A1 (0.38) ALDH1A1MAPTTSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0752625-B1 Copolymers useful as charge injection barrier materials for photoreceptor HEWLETT PACKARD CO (US) 2000-11-15 EP claimed
EP-0752625-A2 Copolymers useful as charge injection barrier materials for photoreceptor Hewlett-Packard Company (US) 1997-01-08 EP claimed
EP-0752625-B1 Copolymers useful as charge injection barrier materials for photoreceptor HEWLETT PACKARD CO (US) 2000-11-15 EP disclosed
EP-0752625-A2 Copolymers useful as charge injection barrier materials for photoreceptor Hewlett-Packard Company (US) 1997-01-08 EP disclosed