Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300028 | 0.80 | CYP2C19 (0.33) | KCNH2GRIN2BCYP2C19HRH3 | |
| SCHEMBL19625756 | 0.68 | HPGD (0.40) | HRH3 | |
| SCHEMBL21946897 | 0.68 | CHRM5 (0.51) | RAB9APADI1PADI4 | |
| SCHEMBL8184493 | 0.67 | KCNH2 (0.39) | KCNH2GRIN2B | |
| SCHEMBL20179968 | 0.66 | CHRM5 (0.50) | RAB9APADI1PADI4 | |
| SCHEMBL21695211 | 0.66 | CHRM5 (0.50) | RAB9APADI1PADI4 | |
| SCHEMBL9052473 | 0.66 | OPRM1 (0.38) | — | |
| SCHEMBL19450983 | 0.65 | CHRM5 (0.41) | RAB9APADI1PADI4 | |
| SCHEMBL27510467 | 0.65 | HRH3 (0.33) | HRH3 | |
| SCHEMBL27295498 | 0.65 | SLC6A1 (0.38) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895475-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0895475-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-02-10 | — | — | EP | disclosed |
| WO-1997024122-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |