Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972994 | 0.76 | PTGS1 (0.32) | PTGS1PTGS2XDH | |
| SCHEMBL6269255 | 0.72 | PTGS1 (0.30) | PTGS1PTGS2 | |
| SCHEMBL6649598 | 0.71 | ALDH1A1 (0.40) | PTGS1PTGS2XDH | |
| SCHEMBL6269251 | 0.69 | KDM4E (0.30) | — | |
| SCHEMBL8316430 | 0.66 | — | — | |
| SCHEMBL8313248 | 0.66 | — | — | |
| SCHEMBL8316624 | 0.66 | KDM4E (0.30) | — | |
| SCHEMBL8124934 | 0.66 | PDK2 (0.30) | — | |
| SCHEMBL6269249 | 0.65 | MLYCD (0.32) | — | |
| SCHEMBL8121161 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655448-B1 | BENZOPYRAN AND BENZOXAZINE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5977167-A | Benzopyran and benzoxazine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5874446-A | ANTIASTHMATICS, ANTIEPILEPSY AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-02-23 | — | — | US | disclosed |
| US-5614633-A | POTASSIUM CHANNEL ACTIVATOR | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0655448-A1 | BENZOPYRAN AND BENZOXAZINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-31 | — | — | EP | disclosed |