Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.46 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677695 | 0.90 | KCNMA1 (0.53) | KCNMA1ARPDK1PDK2PDK3 | |
| SCHEMBL694246 | 0.78 | NPSR1 (0.66) | KCNMA1MEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL8129874 | 0.77 | KMT2A (0.58) | KCNMA1PDK1PDK2PDK3PDK4 | |
| SCHEMBL12350643 | 0.77 | MAPK1 (0.53) | KCNMA1ARPDK1PDK2PDK3 | |
| Acetic Acid SCHEMBL27684276 | 0.76 | MAPT (0.62) | KCNMA1KMT2ANPSR1RXFP1ABCB1 | |
| SCHEMBL14376787 | 0.75 | KCNMA1 (0.58) | KCNMA1ARPDK1PDK2PDK3 | |
| SCHEMBL27810682 | 0.75 | KCNMA1 (0.53) | KCNMA1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL8751610 | 0.75 | KCNMA1 (0.56) | KCNMA1MEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL8469198 | 0.74 | KCNMA1 (0.50) | KCNMA1MEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL2884065 | 0.73 | ALDH1A1 (0.59) | KCNMA1PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054889-A1 | NEW OXAZOLIDINONES WITH AZOL-CONTAINING TRICYCLES | Bayer Aktiengesellschaft (DE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999040094-A1 | AGENT FOR SEALING METALLIC GROUND COATS, ESPECIALLY GROUND COATS CONSISTING OF ZINC OR ZINC ALLOYS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-12 | — | — | WO | disclosed |