Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 9/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096106 | 0.90 | ROCK2 (0.59) | ROCK2RAB9AGAAROCK1SLC6A2 | |
| SCHEMBL8122588 | 0.90 | ROCK2 (0.57) | ROCK2RAB9AMAPTROCK1 | |
| SCHEMBL8122787 | 0.85 | RAB9A (0.48) | ROCK2RAB9AGAASLC6A2SLC6A3 | |
| SCHEMBL8133659 | 0.85 | ROCK2 (0.59) | ROCK2RAB9AROCK1SLC6A2SLC6A3 | |
| SCHEMBL8131443 | 0.85 | ROCK2 (0.46) | ROCK2RAB9AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL8135411 | 0.84 | RAB9A (0.63) | ROCK2RAB9AROCK1SLC6A2SLC6A3 | |
| SCHEMBL7094100 | 0.83 | ROCK2 (0.50) | ROCK2RAB9AMAPTCNR2GAA | |
| SCHEMBL8130038 | 0.81 | ROCK2 (0.53) | ROCK2RAB9AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL8134906 | 0.81 | ROCK2 (0.53) | ROCK2RAB9AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL8134903 | 0.81 | ROCK2 (0.53) | ROCK2RAB9AKDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720601-B1 | GASTRIN AND CCK RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2000-10-25 | — | — | EP | disclosed |
| US-5919829-A | Gastrin and cck receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| US-5795907-A | Gastin and CCK receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1998-08-18 | — | — | US | disclosed |