Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100245 | 0.98 | ALDH1A1 (0.48) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL799646 | 0.98 | ALDH1A1 (0.53) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL17124349 | 0.98 | ALDH1A1 (0.53) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL14803668 | 0.96 | ALDH1A1 (0.52) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL17124347 | 0.96 | ALDH1A1 (0.50) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL14296727 | 0.96 | ALDH1A1 (0.50) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL14803736 | 0.94 | ALDH1A1 (0.48) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL14296741 | 0.92 | DGKA (0.48) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL12677631 | 0.89 | DGKA (0.44) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL14016564 | 0.89 | DGKA (0.59) | ALDH1A1DGKAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897168-B2 | Implantable medical devices having controlled release biodegradable polymer coatings ofof polylactone copolymers based on gamma-butyrolactone; drug delivery systems; controlling in situ drug release; adjustable physical properties; durability. elasticity; vascular stents; offset surgical side-effects | MEDTRONIC VASCULAR, INC. (US) | 2011-03-01 | — | — | US | disclosed |