Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16059778 | 0.79 | ALDH1A1 (0.53) | MAOAMAOBHIF1AALDH1A1DPP4 | |
| SCHEMBL6706478 | 0.79 | ALDH1A1 (0.53) | MAOAMAOBHIF1AALDH1A1DPP4 | |
| SCHEMBL16060230 | 0.79 | ALDH1A1 (0.53) | MAOAMAOBHIF1AALDH1A1DPP4 | |
| Hydrochloric Acid SCHEMBL6706475 | 0.78 | ALDH1A1 (0.55) | MAOAMAOBHIF1AALDH1A1DPP4 | |
| Hydrochloric Acid SCHEMBL4037085 | 0.78 | ALDH1A1 (0.55) | MAOAMAOBHIF1AALDH1A1DPP4 | |
| Hydrochloric Acid SCHEMBL29728759 | 0.78 | ALDH1A1 (0.55) | MAOAMAOBHIF1AALDH1A1DPP4 | |
| Hydrochloric Acid SCHEMBL16059777 | 0.78 | ALDH1A1 (0.55) | MAOAMAOBHIF1AALDH1A1DPP4 | |
| SCHEMBL1717077 | 0.76 | ALDH1A1 (0.56) | MAPK8MAOAMAOBALDH1A1GAA | |
| SCHEMBL15160743 | 0.76 | MAOA (0.43) | MAPK8MAOAMAOBHIF1ADPP4 | |
| SCHEMBL30639470 | 0.76 | ALDH1A1 (0.56) | MAPK8MAOAMAOBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046331-A | Imidazolones and their use in treating benign prostatic hyperplasia and other disorders | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-04-04 | — | — | US | disclosed |