Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.61 |
| ▸ | OGT | O15294 | 1/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.53 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 3/20 | 0.47 |
| ▸ | NOS2 | P35228 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14448380 | 0.77 | F2 (0.56) | NOS1OGTPDE3BPDE3AKMO | |
| SCHEMBL2149352 | 0.76 | NOS1 (0.61) | NOS1OGTPDE3BPDE3AKMO | |
| SCHEMBL981594 | 0.76 | NOS1 (0.61) | NOS1OGTPDE3BPDE3AKMO | |
| SCHEMBL1762301 | 0.76 | NOS1 (0.61) | NOS1OGTPDE3BPDE3AKMO | |
| SCHEMBL11597370 | 0.76 | NOS1 (0.61) | NOS1OGTPDE3BPDE3AKMO | |
| SCHEMBL244119 | 0.76 | NOS1 (1.00) | NOS1OGTPDE3BPDE3AKMO | |
| SCHEMBL2058961 | 0.76 | NOS1 (0.61) | NOS1OGTPDE3BPDE3AKMO | |
| SCHEMBL1519891 | 0.76 | NOS1 (0.72) | NOS1OGTPDE3BPDE3AKMO | |
| SCHEMBL993598 | 0.76 | NOS1 (0.61) | NOS1OGTPDE3BPDE3AKMO | |
| SCHEMBL118727 | 0.76 | NOS1 (0.61) | NOS1OGTPDE3BPDE3AKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |