Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 20/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 19/20 | 1.00 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127311 | 0.82 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL8131063 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8124513 | 0.78 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8118109 | 0.78 | MTNR1A (0.64) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL7022296 | 0.78 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8133099 | 0.77 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8133068 | 0.77 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8133389 | 0.77 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| SCHEMBL8130371 | 0.76 | MTNR1A (0.73) | MTNR1AMTNR1B | |
| SCHEMBL8132594 | 0.76 | MTNR1A (0.73) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147110-A | MELATONINERGIC AGENTS; SLEEP, EATING, CENTRAL NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-14 | — | — | US | disclosed |
| EP-0926145-A1 | Napthalene compounds, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-30 | — | — | EP | disclosed |