Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118628 | 0.78 | MTNR1A (0.44) | MTNR1AMTNR1BRAB9ANPC1KDM4E | |
| SCHEMBL8133947 | 0.77 | MTNR1A (0.58) | MTNR1AMTNR1BRAB9ANPC1KDM4E | |
| SCHEMBL8131732 | 0.77 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8128784 | 0.75 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL8117486 | 0.75 | MTNR1A (0.38) | MTNR1AMTNR1BRAB9ANPC1POLB | |
| SCHEMBL8125047 | 0.74 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL8132270 | 0.74 | MTNR1A (0.61) | MTNR1AMTNR1BRAB9ANPC1KDM4E | |
| SCHEMBL8127457 | 0.74 | MTNR1A (0.63) | MTNR1AMTNR1BNQO1 | |
| SCHEMBL8127257 | 0.73 | MTNR1A (0.63) | MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL8124550 | 0.73 | MTNR1A (0.48) | MTNR1AMTNR1BRAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147110-A | MELATONINERGIC AGENTS; SLEEP, EATING, CENTRAL NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-14 | — | — | US | disclosed |
| EP-0926145-A1 | Napthalene compounds, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-30 | — | — | EP | disclosed |